Intranasal administration of BReC-CoV-2 COVID-19 vaccine protects K18-hACE2 mice against lethal SARS-CoV-2 challenge

SARS-CoV-2 is a viral respiratory pathogen responsible for the current global pandemic and the disease that causes COVID-19. All current WHO approved COVID-19 vaccines are administered through the muscular route. We have developed a prototype two-dose vaccine (BReC-CoV-2) by combining the Receptor B...

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Detalles Bibliográficos
Autores principales: Wong, Ting Y., Lee, Katherine S., Russ, Brynnan P., Horspool, Alexander M., Kang, Jason, Winters, Michael T., Allison Wolf, M., Rader, Nathaniel A., Miller, Olivia A., Shiflett, Morgane, Izac, Jerilyn, Varisco, David, Sen-Kilic, Emel, Cunningham, Casey, Cooper, Melissa, Cyphert, Holly A., Barbier, Mariette, Martinez, Ivan, Bevere, Justin R., Ernst, Robert K., Damron, F. Heath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8921182/
https://www.ncbi.nlm.nih.gov/pubmed/35288576
http://dx.doi.org/10.1038/s41541-022-00451-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8921182/
https://www.ncbi.nlm.nih.gov/pubmed/35288576
http://dx.doi.org/10.1038/s41541-022-00451-7

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