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A systematic review and meta-analysis of gene therapy with hematopoietic stem and progenitor cells for monogenic disorders

Ex-vivo gene therapy (GT) with hematopoietic stem and progenitor cells (HSPCs) engineered with integrating vectors is a promising treatment for monogenic diseases, but lack of centralized databases is hampering an overall outcomes assessment. Here we aim to provide a comprehensive assessment of the...

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Detalles Bibliográficos
Autores principales:	Tucci, Francesca, Galimberti, Stefania, Naldini, Luigi, Valsecchi, Maria Grazia, Aiuti, Alessandro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8921234/ https://www.ncbi.nlm.nih.gov/pubmed/35288539 http://dx.doi.org/10.1038/s41467-022-28762-2

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