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A novel hybrid peptide composed of LfcinB6 and KR-12-a4 with enhanced antimicrobial, anti-inflammatory and anti-biofilm activities

Hybridizing two known antimicrobial peptides (AMPs) is a simple and effective strategy for designing antimicrobial agents with enhanced cell selectivity against bacterial cells. Here, we generated a hybrid peptide Lf-KR in which LfcinB6 and KR-12-a4 were linked with a Pro hinge to obtain a novel AMP...

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Detalles Bibliográficos
Autores principales:	Ajish, Chelladurai, Yang, Sungtae, Kumar, S. Dinesh, Kim, Eun Young, Min, Hye Jung, Lee, Chul Won, Shin, Sung-Heui, Shin, Song Yub
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8921290/ https://www.ncbi.nlm.nih.gov/pubmed/35288606 http://dx.doi.org/10.1038/s41598-022-08247-4

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