Cargando…
Quantitative measurements of esophageal varices using computed tomography for prediction of severe varices and the risk of bleeding: a preliminary study
BACKGROUND: We aimed to assess whether the quantitative parameters of esophageal varices (EV) based on computed tomography (CT) can noninvasively predict severe EV and the risk of esophageal variceal bleeding (EVB). METHODS: A total of 136 endoscopically confirmed EV patients were included in this r...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Vienna
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8921428/ https://www.ncbi.nlm.nih.gov/pubmed/35286491 http://dx.doi.org/10.1186/s13244-022-01189-5 |
_version_ | 1784669322653728768 |
---|---|
author | Wan, Shang He, Yuhao Zhang, Xin Wei, Yi Song, Bin |
author_facet | Wan, Shang He, Yuhao Zhang, Xin Wei, Yi Song, Bin |
author_sort | Wan, Shang |
collection | PubMed |
description | BACKGROUND: We aimed to assess whether the quantitative parameters of esophageal varices (EV) based on computed tomography (CT) can noninvasively predict severe EV and the risk of esophageal variceal bleeding (EVB). METHODS: A total of 136 endoscopically confirmed EV patients were included in this retrospective study and were divided into a non-conspicuous (mild-to-moderate EV, n = 30) and a conspicuous EV group (severe EV, n = 106), a bleeding (n = 89) and a non-bleeding group (n = 47). EV grade (EVG), EV diameter (EVD), cross-sectional surface area (CSA), EV volume (EVV), spleen volume (SV), splenic vein (SNV), portal vein (PV), diameter of left gastric vein (DLGV), and the opening type of LGV were measured independently using 3D-slicer. Univariate and multivariate logistic analysis were used to determine the independent factors and the receiver operating characteristic (ROC) curves were performed to evaluate the diagnostic performance. RESULTS: The difference of EVG, EVD, CSA, EVV, DLGV, SNV between the conspicuous and non-conspicuous EV group were statistically significant (p < 0.05), area under the curves (AUCs) of them for predicting severe EV were 0.72, 0.772, 0.704, 0.768, 0.707, 0.65, with corresponding sensitivities of 70.3%, 63.5%, 50%, 74.3%, 52.7%, 48.6%, specificities of 71.4%, 85.7%, 100%, 71.4%, 81%, 81%, respectively. EVG, CSA (odds ratio 3.258, 95% CI 1.597–6.647; 1.029, 95% CI 1.008–1.050) were found to be independent predictive factors. However, there was no significant difference of the included indices between the bleeding and non-bleeding group (p > 0.05). CONCLUSIONS: CT can be used as a noninvasive method to predict the severity of EV, which may reduce the invasive screening of endoscopy. |
format | Online Article Text |
id | pubmed-8921428 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Springer Vienna |
record_format | MEDLINE/PubMed |
spelling | pubmed-89214282022-03-25 Quantitative measurements of esophageal varices using computed tomography for prediction of severe varices and the risk of bleeding: a preliminary study Wan, Shang He, Yuhao Zhang, Xin Wei, Yi Song, Bin Insights Imaging Original Article BACKGROUND: We aimed to assess whether the quantitative parameters of esophageal varices (EV) based on computed tomography (CT) can noninvasively predict severe EV and the risk of esophageal variceal bleeding (EVB). METHODS: A total of 136 endoscopically confirmed EV patients were included in this retrospective study and were divided into a non-conspicuous (mild-to-moderate EV, n = 30) and a conspicuous EV group (severe EV, n = 106), a bleeding (n = 89) and a non-bleeding group (n = 47). EV grade (EVG), EV diameter (EVD), cross-sectional surface area (CSA), EV volume (EVV), spleen volume (SV), splenic vein (SNV), portal vein (PV), diameter of left gastric vein (DLGV), and the opening type of LGV were measured independently using 3D-slicer. Univariate and multivariate logistic analysis were used to determine the independent factors and the receiver operating characteristic (ROC) curves were performed to evaluate the diagnostic performance. RESULTS: The difference of EVG, EVD, CSA, EVV, DLGV, SNV between the conspicuous and non-conspicuous EV group were statistically significant (p < 0.05), area under the curves (AUCs) of them for predicting severe EV were 0.72, 0.772, 0.704, 0.768, 0.707, 0.65, with corresponding sensitivities of 70.3%, 63.5%, 50%, 74.3%, 52.7%, 48.6%, specificities of 71.4%, 85.7%, 100%, 71.4%, 81%, 81%, respectively. EVG, CSA (odds ratio 3.258, 95% CI 1.597–6.647; 1.029, 95% CI 1.008–1.050) were found to be independent predictive factors. However, there was no significant difference of the included indices between the bleeding and non-bleeding group (p > 0.05). CONCLUSIONS: CT can be used as a noninvasive method to predict the severity of EV, which may reduce the invasive screening of endoscopy. Springer Vienna 2022-03-14 /pmc/articles/PMC8921428/ /pubmed/35286491 http://dx.doi.org/10.1186/s13244-022-01189-5 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Original Article Wan, Shang He, Yuhao Zhang, Xin Wei, Yi Song, Bin Quantitative measurements of esophageal varices using computed tomography for prediction of severe varices and the risk of bleeding: a preliminary study |
title | Quantitative measurements of esophageal varices using computed tomography for prediction of severe varices and the risk of bleeding: a preliminary study |
title_full | Quantitative measurements of esophageal varices using computed tomography for prediction of severe varices and the risk of bleeding: a preliminary study |
title_fullStr | Quantitative measurements of esophageal varices using computed tomography for prediction of severe varices and the risk of bleeding: a preliminary study |
title_full_unstemmed | Quantitative measurements of esophageal varices using computed tomography for prediction of severe varices and the risk of bleeding: a preliminary study |
title_short | Quantitative measurements of esophageal varices using computed tomography for prediction of severe varices and the risk of bleeding: a preliminary study |
title_sort | quantitative measurements of esophageal varices using computed tomography for prediction of severe varices and the risk of bleeding: a preliminary study |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8921428/ https://www.ncbi.nlm.nih.gov/pubmed/35286491 http://dx.doi.org/10.1186/s13244-022-01189-5 |
work_keys_str_mv | AT wanshang quantitativemeasurementsofesophagealvaricesusingcomputedtomographyforpredictionofseverevaricesandtheriskofbleedingapreliminarystudy AT heyuhao quantitativemeasurementsofesophagealvaricesusingcomputedtomographyforpredictionofseverevaricesandtheriskofbleedingapreliminarystudy AT zhangxin quantitativemeasurementsofesophagealvaricesusingcomputedtomographyforpredictionofseverevaricesandtheriskofbleedingapreliminarystudy AT weiyi quantitativemeasurementsofesophagealvaricesusingcomputedtomographyforpredictionofseverevaricesandtheriskofbleedingapreliminarystudy AT songbin quantitativemeasurementsofesophagealvaricesusingcomputedtomographyforpredictionofseverevaricesandtheriskofbleedingapreliminarystudy |