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Proteomic analysis of heat-stable proteins revealed an increased proportion of proteins with compositionally biased regions
Intrinsically disordered proteins (IDPs) have been in the spotlight for their unique properties, such as their lack of secondary structures and low sequence complexity. Alpha-synuclein and tau are representative disease-related IDPs with low complexity regions in their sequences, accumulating in the...
Autores principales: | Park, Hongsun, Yamanaka, Tomoyuki, Nukina, Nobuyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8921518/ https://www.ncbi.nlm.nih.gov/pubmed/35289333 http://dx.doi.org/10.1038/s41598-022-08044-z |
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