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Proteomic analysis of heat-stable proteins revealed an increased proportion of proteins with compositionally biased regions

Intrinsically disordered proteins (IDPs) have been in the spotlight for their unique properties, such as their lack of secondary structures and low sequence complexity. Alpha-synuclein and tau are representative disease-related IDPs with low complexity regions in their sequences, accumulating in the...

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Detalles Bibliográficos
Autores principales: Park, Hongsun, Yamanaka, Tomoyuki, Nukina, Nobuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8921518/
https://www.ncbi.nlm.nih.gov/pubmed/35289333
http://dx.doi.org/10.1038/s41598-022-08044-z

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