PRODeepSyn: predicting anticancer synergistic drug combinations by embedding cell lines with protein–protein interaction network

Although drug combinations in cancer treatment appear to be a promising therapeutic strategy with respect to monotherapy, it is arduous to discover new synergistic drug combinations due to the combinatorial explosion. Deep learning technology holds immense promise for better prediction of in vitro s...

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Detalles Bibliográficos
Autores principales: Wang, Xiaowen, Zhu, Hongming, Jiang, Yizhi, Li, Yulong, Tang, Chen, Chen, Xiaohan, Li, Yunjie, Liu, Qi, Liu, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Problem Solving Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8921631/
https://www.ncbi.nlm.nih.gov/pubmed/35043159
http://dx.doi.org/10.1093/bib/bbab587

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8921631/
https://www.ncbi.nlm.nih.gov/pubmed/35043159
http://dx.doi.org/10.1093/bib/bbab587

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