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Comprehensive evaluation of noise reduction methods for single-cell RNA sequencing data
Normalization and batch correction are critical steps in processing single-cell RNA sequencing (scRNA-seq) data, which remove technical effects and systematic biases to unmask biological signals of interest. Although a number of computational methods have been developed, there is no guidance for cho...
Autores principales: | Chu, Shih-Kai, Zhao, Shilin, Shyr, Yu, Liu, Qi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8921632/ https://www.ncbi.nlm.nih.gov/pubmed/35048125 http://dx.doi.org/10.1093/bib/bbab565 |
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