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Septins tune lipid kinase activity and PI(4,5)P(2) turnover during G-protein–coupled PLC signalling in vivo
Phosphatidylinositol 4,5-bisphosphate [PI(4,5)P(2)] hydrolysis by phospholipase C (PLC) is a conserved mechanism of signalling. Given the low abundance of PI(4,5)P(2), its hydrolysis needs to be coupled to resynthesis to ensure continued PLC activity; however, the mechanism by which depletion is cou...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Life Science Alliance LLC
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8921834/ https://www.ncbi.nlm.nih.gov/pubmed/35277468 http://dx.doi.org/10.26508/lsa.202101293 |