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Targeting CD96 overcomes PD-1 blockade resistance by enhancing CD8+ TIL function in cervical cancer
BACKGROUND: Novel therapies are needed to treat recurrent and advanced cervical cancer (CC), as their prognosis remains very poor. Although therapies targeting the programmed cell death protein 1 (PD-1) pathway have been approved for CC, a large subset of patients exhibit innate resistance. Using ch...
Autores principales: | Wang, Yumeng, Wang, Congwen, Qiu, Junjun, Qu, Xinyu, Peng, Jing, Lu, Chong, Zhang, Meng, Zhang, Mingxing, Qi, Xingling, Li, Guiling, Hua, Keqin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8921917/ https://www.ncbi.nlm.nih.gov/pubmed/35288463 http://dx.doi.org/10.1136/jitc-2021-003667 |
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