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ZEB1 transcription factor promotes immune escape in melanoma

BACKGROUND: The efficacy of immunotherapies in metastatic melanoma depends on a robust T cell infiltration. Oncogenic alterations of tumor cells have been associated to T cell exclusion. Identifying novel cancer cell-intrinsic non-genetic mechanisms of immune escape, the targeting of which would rei...

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Detalles Bibliográficos
Autores principales:	Plaschka, Maud, Benboubker, Valentin, Grimont, Maxime, Berthet, Justine, Tonon, Laurie, Lopez, Jonathan, Le-Bouar, Myrtille, Balme, Brigitte, Tondeur, Garance, de la Fouchardière, Arnaud, Larue, Lionel, Puisieux, Alain, Grinberg-Bleyer, Yenkel, Bendriss-Vermare, Nathalie, Dubois, Bertrand, Caux, Christophe, Dalle, Stéphane, Caramel, Julie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2022
Materias:	Basic Tumor Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8921918/ https://www.ncbi.nlm.nih.gov/pubmed/35288462 http://dx.doi.org/10.1136/jitc-2021-003484

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