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Downregulation of NCL attenuates tumor formation and growth in HeLa cells by targeting the PI3K/AKT pathway

BACKGROUND: Nucleolin (NCL, C23) is a multifunctional phosphoprotein that plays a vital role in modulating the survival, proliferationand apoptosis of cancer cells. However, the effects of NCL on cervical cancer and the underlying mechanisms behind this are poorly understood. METHODS: Lentiviral tra...

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Detalles Bibliográficos
Autores principales: Ying, Jun, Pan, Ruowang, Tang, Zhouhao, Zhu, Jiayin, Ren, Ping, Lou, Yang, Zhang, Enyong, Huang, Dadao, Hu, Penghong, Li, Dong, Bao, Qiyu, Li, Peizhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8921942/
https://www.ncbi.nlm.nih.gov/pubmed/35128835
http://dx.doi.org/10.1002/cam4.4569