How Does Blood-Retinal Barrier Breakdown Relate to Death and Disability in Pediatric Cerebral Malaria?

BACKGROUND: In cerebral malaria, the retina can be used to understand disease pathogenesis. The mechanisms linking sequestration, brain swelling, and death remain poorly understood. We hypothesized that retinal vascular leakage would be associated with brain swelling. METHODS: We used retinal angiog...

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Detalles Bibliográficos
Autores principales: MacCormick, Ian J C, Barrera, Valentina, Beare, Nicholas A V, Czanner, Gabriela, Potchen, Michael, Kampondeni, Samuel, Heyderman, Robert S, Craig, Alister G, Molyneux, Malcolm E, Mallewa, Macpherson, White, Valerie A, Milner, Dan, Hiscott, Paul, Taylor, Terrie E, Seydel, Karl B, Harding, Simon P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Major Articles and Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922008/
https://www.ncbi.nlm.nih.gov/pubmed/32845969
http://dx.doi.org/10.1093/infdis/jiaa541

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