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The schizophrenia risk gene Map2k7 regulates responding in a novel contingency-shifting rodent touchscreen gambling task

In schizophrenia, subjects show reduced ability to evaluate and update risk/reward contingencies, showing correspondingly suboptimal performance in the Iowa gambling task. JNK signalling gene variants are associated with schizophrenia risk, and JNK modulates aspects of cognition. We therefore studie...

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Detalles Bibliográficos
Autores principales: Openshaw, Rebecca L., Pratt, Judith A., Morris, Brian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922023/
https://www.ncbi.nlm.nih.gov/pubmed/35275161
http://dx.doi.org/10.1242/dmm.049310

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