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A Matrigel-based 3D construct of SH-SY5Y cells models the α-synuclein pathologies of Parkinson's disease

Parkinson's disease (PD) is associated with α-synuclein-based Lewy body pathology, which has been difficult to observe in conventional two-dimensional (2D) cell culture and even in animal models. We herein aimed to develop a three-dimensional (3D) cellular model of PD to recapitulate the α-synu...

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Detalles Bibliográficos
Autores principales:	Li, Zhao-Feng, Cui, Lei, Jin, Mi-Mi, Hu, Dong-Yan, Hou, Xiao-Gang, Liu, Shu-Shu, Zhang, Xiong, Zhu, Jian-Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists Ltd 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922027/ https://www.ncbi.nlm.nih.gov/pubmed/35023548 http://dx.doi.org/10.1242/dmm.049125

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