Comment on: The m6A Reader IGF2BP2 Regulates Macrophage Phenotypic Activation and Inflammatory Diseases by Stabilizing TSC1 and PPARγ

Recently, first insights into the regulation and the role of the RNA‐binding protein IMP2 in macrophage activation have been published by Wang et al. This study addresses differences in the regulation of IMP2 between the human and murine system. While the expression of IMP2 in anti‐inflammatory macr...

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Autores principales: Schymik, Hanna S., Dahlem, Charlotte, Barghash, Ahmad, Kiemer, Alexandra K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Comment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922093/
https://www.ncbi.nlm.nih.gov/pubmed/35038236
http://dx.doi.org/10.1002/advs.202104372
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author Schymik, Hanna S.
Dahlem, Charlotte
Barghash, Ahmad
Kiemer, Alexandra K.
author_facet Schymik, Hanna S.
Dahlem, Charlotte
Barghash, Ahmad
Kiemer, Alexandra K.
author_sort Schymik, Hanna S.
collection PubMed
description Recently, first insights into the regulation and the role of the RNA‐binding protein IMP2 in macrophage activation have been published by Wang et al. This study addresses differences in the regulation of IMP2 between the human and murine system. While the expression of IMP2 in anti‐inflammatory macrophages is synchronous in mice and men, IMP2 expression is regulated differently in inflammatory macrophages.
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spelling pubmed-89220932022-03-21 Comment on: The m6A Reader IGF2BP2 Regulates Macrophage Phenotypic Activation and Inflammatory Diseases by Stabilizing TSC1 and PPARγ Schymik, Hanna S. Dahlem, Charlotte Barghash, Ahmad Kiemer, Alexandra K. Adv Sci (Weinh) Comment Recently, first insights into the regulation and the role of the RNA‐binding protein IMP2 in macrophage activation have been published by Wang et al. This study addresses differences in the regulation of IMP2 between the human and murine system. While the expression of IMP2 in anti‐inflammatory macrophages is synchronous in mice and men, IMP2 expression is regulated differently in inflammatory macrophages. John Wiley and Sons Inc. 2022-01-17 /pmc/articles/PMC8922093/ /pubmed/35038236 http://dx.doi.org/10.1002/advs.202104372 Text en © 2022 The Authors. Advanced Science published by Wiley‐VCH GmbH https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Comment
Schymik, Hanna S.
Dahlem, Charlotte
Barghash, Ahmad
Kiemer, Alexandra K.
Comment on: The m6A Reader IGF2BP2 Regulates Macrophage Phenotypic Activation and Inflammatory Diseases by Stabilizing TSC1 and PPARγ
title Comment on: The m6A Reader IGF2BP2 Regulates Macrophage Phenotypic Activation and Inflammatory Diseases by Stabilizing TSC1 and PPARγ
title_full Comment on: The m6A Reader IGF2BP2 Regulates Macrophage Phenotypic Activation and Inflammatory Diseases by Stabilizing TSC1 and PPARγ
title_fullStr Comment on: The m6A Reader IGF2BP2 Regulates Macrophage Phenotypic Activation and Inflammatory Diseases by Stabilizing TSC1 and PPARγ
title_full_unstemmed Comment on: The m6A Reader IGF2BP2 Regulates Macrophage Phenotypic Activation and Inflammatory Diseases by Stabilizing TSC1 and PPARγ
title_short Comment on: The m6A Reader IGF2BP2 Regulates Macrophage Phenotypic Activation and Inflammatory Diseases by Stabilizing TSC1 and PPARγ
title_sort comment on: the m6a reader igf2bp2 regulates macrophage phenotypic activation and inflammatory diseases by stabilizing tsc1 and pparγ
topic Comment
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922093/
https://www.ncbi.nlm.nih.gov/pubmed/35038236
http://dx.doi.org/10.1002/advs.202104372
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