Targeting Cancer Metabolism Plasticity with JX06 Nanoparticles via Inhibiting PDK1 Combined with Metformin for Endometrial Cancer Patients with Diabetes

Diabetes is closely related to the occurrence of endometrial cancer (EC) and its poor prognosis. However, there is no effective clinical treatment for EC patients with diabetes (patient(EC+/dia+)). To explore new therapeutic targets, Ishikawa is cultured with high glucose (Ishikawa(HG)) mimicking hy...

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Detalles Bibliográficos
Autores principales: Yang, Xiao, Cheng, Yuan, Zhou, Jingyi, Zhang, Lingpu, Li, Xingchen, Wang, Zhiqi, Yin, Shenyi, Zhai, LiRong, Huang, Ting, Wu, Xiaotong, Shen, Boqiang, Dong, Yangyang, Zhao, Lijun, Chi, Yujing, Jia, Yuanyuan, Wang, Jiaqi, He, Yijiao, Dong, Xiying, Xiao, Haihua, Wang, Jianliu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922133/
https://www.ncbi.nlm.nih.gov/pubmed/35064767
http://dx.doi.org/10.1002/advs.202104472

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