Coinfection by Aspergillus and Mucoraceae Species in Two Cases of Acute Rhinosinusitis as a Complication of COVID-19

Acute invasive fungal rhinosinusitis (AIFR) is a life-threatening infection often found in immunocompromised patients. In the COVID-19 era, reports of AIFR have emerged, with high mortality and morbidity rate. This paper presents two cases of COVID-19 associated AIFR with the combined proven fungal...

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Autores principales: Tabarsi, Payam, Sharifynia, Somayeh, Pourabdollah Toutkaboni, Mihan, Abtahian, Zahra, Rahdar, Mohammad, Mirahmadian, Arefeh Sadat, Hakamifard, Atousa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922146/
https://www.ncbi.nlm.nih.gov/pubmed/35299783
http://dx.doi.org/10.1155/2022/8114388
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author Tabarsi, Payam
Sharifynia, Somayeh
Pourabdollah Toutkaboni, Mihan
Abtahian, Zahra
Rahdar, Mohammad
Mirahmadian, Arefeh Sadat
Hakamifard, Atousa
author_facet Tabarsi, Payam
Sharifynia, Somayeh
Pourabdollah Toutkaboni, Mihan
Abtahian, Zahra
Rahdar, Mohammad
Mirahmadian, Arefeh Sadat
Hakamifard, Atousa
author_sort Tabarsi, Payam
collection PubMed
description Acute invasive fungal rhinosinusitis (AIFR) is a life-threatening infection often found in immunocompromised patients. In the COVID-19 era, reports of AIFR have emerged, with high mortality and morbidity rate. This paper presents two cases of COVID-19 associated AIFR with the combined proven fungal etiology of Aspergillus flavus and Rhizopus arrhizus in case 1 and Aspergillus fumigatus and Rhizopus arrhizus in case 2. Both patients received liposomal amphotericin B then posaconazole combined with aggressive surgical debridement of necrotic tissues with a favorable clinical outcome. Mixed etiology AIFR can influence the outcome; hence, further studies are required upon this new threat.
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spelling pubmed-89221462022-03-16 Coinfection by Aspergillus and Mucoraceae Species in Two Cases of Acute Rhinosinusitis as a Complication of COVID-19 Tabarsi, Payam Sharifynia, Somayeh Pourabdollah Toutkaboni, Mihan Abtahian, Zahra Rahdar, Mohammad Mirahmadian, Arefeh Sadat Hakamifard, Atousa Case Rep Med Case Report Acute invasive fungal rhinosinusitis (AIFR) is a life-threatening infection often found in immunocompromised patients. In the COVID-19 era, reports of AIFR have emerged, with high mortality and morbidity rate. This paper presents two cases of COVID-19 associated AIFR with the combined proven fungal etiology of Aspergillus flavus and Rhizopus arrhizus in case 1 and Aspergillus fumigatus and Rhizopus arrhizus in case 2. Both patients received liposomal amphotericin B then posaconazole combined with aggressive surgical debridement of necrotic tissues with a favorable clinical outcome. Mixed etiology AIFR can influence the outcome; hence, further studies are required upon this new threat. Hindawi 2022-03-14 /pmc/articles/PMC8922146/ /pubmed/35299783 http://dx.doi.org/10.1155/2022/8114388 Text en Copyright © 2022 Payam Tabarsi et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Tabarsi, Payam
Sharifynia, Somayeh
Pourabdollah Toutkaboni, Mihan
Abtahian, Zahra
Rahdar, Mohammad
Mirahmadian, Arefeh Sadat
Hakamifard, Atousa
Coinfection by Aspergillus and Mucoraceae Species in Two Cases of Acute Rhinosinusitis as a Complication of COVID-19
title Coinfection by Aspergillus and Mucoraceae Species in Two Cases of Acute Rhinosinusitis as a Complication of COVID-19
title_full Coinfection by Aspergillus and Mucoraceae Species in Two Cases of Acute Rhinosinusitis as a Complication of COVID-19
title_fullStr Coinfection by Aspergillus and Mucoraceae Species in Two Cases of Acute Rhinosinusitis as a Complication of COVID-19
title_full_unstemmed Coinfection by Aspergillus and Mucoraceae Species in Two Cases of Acute Rhinosinusitis as a Complication of COVID-19
title_short Coinfection by Aspergillus and Mucoraceae Species in Two Cases of Acute Rhinosinusitis as a Complication of COVID-19
title_sort coinfection by aspergillus and mucoraceae species in two cases of acute rhinosinusitis as a complication of covid-19
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922146/
https://www.ncbi.nlm.nih.gov/pubmed/35299783
http://dx.doi.org/10.1155/2022/8114388
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