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The Proinflammatory Cytokines IL-18, IL-21, and IFN-γ Differentially Regulate Liver Inflammation and Anti-Mitochondrial Antibody Level in a Murine Model of Primary Biliary Cholangitis

Primary biliary cholangitis (PBC) is a cholestatic liver disease primarily featured by autoimmune-mediated damage of intrahepatic small- and medium-sized bile ducts. Elevated serum proinflammatory cytokines, serum anti-mitochondrial antibodies (AMAs), liver inflammation, and fibrosis are also hallma...

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Detalles Bibliográficos
Autores principales:	Xu, Ya-Fei, Yao, Yuan, Ma, Min, Yang, Shu-Han, Jiang, Peng, Wang, Jinjun, Tsuneyama, Koichi, Wang, Chan, Liu, Xiangdong, Li, Liang, Lian, Zhe-Xiong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922149/ https://www.ncbi.nlm.nih.gov/pubmed/35300072 http://dx.doi.org/10.1155/2022/7111445

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