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DNA-Dependent Binding of Nargenicin to DnaE1 Inhibits Replication in Mycobacterium tuberculosis

[Image: see text] Natural products provide a rich source of potential antimicrobials for treating infectious diseases for which drug resistance has emerged. Foremost among these diseases is tuberculosis. Assessment of the antimycobacterial activity of nargenicin, a natural product that targets the r...

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Detalles Bibliográficos
Autores principales:	Chengalroyen, Melissa D., Mason, Mandy K., Borsellini, Alessandro, Tassoni, Raffaella, Abrahams, Garth L., Lynch, Sasha, Ahn, Yong-Mo, Ambler, Jon, Young, Katherine, Crowley, Brendan M., Olsen, David B., Warner, Digby F., Barry III, Clifton E., Boshoff, Helena I. M., Lamers, Meindert H., Mizrahi, Valerie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922275/ https://www.ncbi.nlm.nih.gov/pubmed/35143160 http://dx.doi.org/10.1021/acsinfecdis.1c00643

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