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Glomerulus-on-a-Chip: Current Insights and Future Potential Towards Recapitulating Selectively Permeable Filtration Systems
Glomerulopathy, characterized by a dysfunctional glomerular capillary wall, results in proteinuria, leading to end-stage renal failure and poor clinical outcomes, including renal death and increased overall mortality. Conventional glomerulopathy research, including drug discovery, has mostly relied...
Autores principales: | Doi, Kotaro, Kimura, Hiroshi, Matsunaga, Yukiko T, Fujii, Teruo, Nangaku, Masaomi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922329/ https://www.ncbi.nlm.nih.gov/pubmed/35299832 http://dx.doi.org/10.2147/IJNRD.S344725 |
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