N-methyl-d-aspartate receptor subunit 2B on keratinocyte mediates peripheral and central sensitization in chronic post-ischemic pain in male rats

The spinal N-methyl-D-aspartate (NMDA) receptor, and particularly its NR2B subunit, plays a pivotal role in neuropathic pain. However, the role of peripheral NMDA receptor in neuropathic pain is less well understood. We first treated cultured human keratinocytes, HaCaT cells with NMDA or NR2B-specif...

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Detalles Bibliográficos
Autores principales: Xu, Xiaohan, Tao, Xin, Huang, Ping, Lin, Feng, Liu, Qing, Xu, Li, Xu, Jijun, Huang, Yuguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922412/
https://www.ncbi.nlm.nih.gov/pubmed/32032782
http://dx.doi.org/10.1016/j.bbi.2020.02.003

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