Value of M2BP in predicting in‐stent restenosis in patients after coronary drug‐eluting stent implantation

OBJECTIVE: We evaluated the association between plasma levels of mac‐2 binding protein (M2BP) with the risk of in‐stent restenosis (ISR) after percutaneous coronary intervention (PCI). METHODS: Plasma M2BP levels were compared between 258 patients who experienced ISR at 12‐months post‐PCI and 258 pa...

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Autores principales: Yang, Le, Zhu, Haijun, Sun, Yuanyuan, Yan, Pengcheng, Song, Xiaoning, Xu, Fayun, Yuan, Haitao, Chen, Liming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Clinical Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922530/
https://www.ncbi.nlm.nih.gov/pubmed/35032135
http://dx.doi.org/10.1002/clc.23775
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author Yang, Le
Zhu, Haijun
Sun, Yuanyuan
Yan, Pengcheng
Song, Xiaoning
Xu, Fayun
Yuan, Haitao
Chen, Liming
author_facet Yang, Le
Zhu, Haijun
Sun, Yuanyuan
Yan, Pengcheng
Song, Xiaoning
Xu, Fayun
Yuan, Haitao
Chen, Liming
author_sort Yang, Le
collection PubMed
description OBJECTIVE: We evaluated the association between plasma levels of mac‐2 binding protein (M2BP) with the risk of in‐stent restenosis (ISR) after percutaneous coronary intervention (PCI). METHODS: Plasma M2BP levels were compared between 258 patients who experienced ISR at 12‐months post‐PCI and 258 patients, matched for age and sex, without angiographic evidence of ISR. RESULTS: The plasma M2BP level was significantly higher in the ISR than in the non‐ISR group. On multivariate analysis, adjusted for potential clinical, biochemical, and angiography characteristics, M2BP remained as an independent significant predictor of ISR. CONCLUSIONS: M2BP may be an important predictive biomarker of ISR and may be useful in identifying at‐risk patients.
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spelling pubmed-89225302022-03-21 Value of M2BP in predicting in‐stent restenosis in patients after coronary drug‐eluting stent implantation Yang, Le Zhu, Haijun Sun, Yuanyuan Yan, Pengcheng Song, Xiaoning Xu, Fayun Yuan, Haitao Chen, Liming Clin Cardiol Clinical Investigations OBJECTIVE: We evaluated the association between plasma levels of mac‐2 binding protein (M2BP) with the risk of in‐stent restenosis (ISR) after percutaneous coronary intervention (PCI). METHODS: Plasma M2BP levels were compared between 258 patients who experienced ISR at 12‐months post‐PCI and 258 patients, matched for age and sex, without angiographic evidence of ISR. RESULTS: The plasma M2BP level was significantly higher in the ISR than in the non‐ISR group. On multivariate analysis, adjusted for potential clinical, biochemical, and angiography characteristics, M2BP remained as an independent significant predictor of ISR. CONCLUSIONS: M2BP may be an important predictive biomarker of ISR and may be useful in identifying at‐risk patients. John Wiley and Sons Inc. 2022-01-15 /pmc/articles/PMC8922530/ /pubmed/35032135 http://dx.doi.org/10.1002/clc.23775 Text en © 2022 The Authors. Clinical Cardiology published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Investigations
Yang, Le
Zhu, Haijun
Sun, Yuanyuan
Yan, Pengcheng
Song, Xiaoning
Xu, Fayun
Yuan, Haitao
Chen, Liming
Value of M2BP in predicting in‐stent restenosis in patients after coronary drug‐eluting stent implantation
title Value of M2BP in predicting in‐stent restenosis in patients after coronary drug‐eluting stent implantation
title_full Value of M2BP in predicting in‐stent restenosis in patients after coronary drug‐eluting stent implantation
title_fullStr Value of M2BP in predicting in‐stent restenosis in patients after coronary drug‐eluting stent implantation
title_full_unstemmed Value of M2BP in predicting in‐stent restenosis in patients after coronary drug‐eluting stent implantation
title_short Value of M2BP in predicting in‐stent restenosis in patients after coronary drug‐eluting stent implantation
title_sort value of m2bp in predicting in‐stent restenosis in patients after coronary drug‐eluting stent implantation
topic Clinical Investigations
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922530/
https://www.ncbi.nlm.nih.gov/pubmed/35032135
http://dx.doi.org/10.1002/clc.23775
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