Enhanced tumor accumulation and therapeutic efficacy of liposomal drugs through over-threshold dosing

BACKGROUND: Most intravenously administered drug-loaded nanoparticles are taken up by liver Kupffer cells, and only a small portion can accumulate at the tumor, resulting in an unsatisfactory therapeutic efficacy and side effects for chemotherapeutic agents. Tumor-targeted drug delivery proves to be...

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Detalles Bibliográficos
Autores principales: Ao, Hui, Wang, Zhuo, Lu, Likang, Ma, Hongwei, Li, Haowen, Fu, Jingxin, Li, Manzhen, Han, Meihua, Guo, Yifei, Wang, Xiangtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922779/
https://www.ncbi.nlm.nih.gov/pubmed/35292036
http://dx.doi.org/10.1186/s12951-022-01349-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922779/
https://www.ncbi.nlm.nih.gov/pubmed/35292036
http://dx.doi.org/10.1186/s12951-022-01349-1

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