Homer1 promotes the conversion of A1 astrocytes to A2 astrocytes and improves the recovery of transgenic mice after intracerebral hemorrhage

BACKGROUND: Inflammation induced by intracerebral hemorrhage (ICH) is one of the main causes of the high mortality and poor prognosis of patients with ICH. A1 astrocytes are closely associated with neuroinflammation and neurotoxicity, whereas A2 astrocytes are neuroprotective. Homer scaffolding prot...

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Detalles Bibliográficos
Autores principales: Fei, Xiaowei, Dou, Ya-nan, Wang, Li, Wu, Xiuquan, Huan, Yu, Wu, Shuang, He, Xin, Lv, Weihao, Wei, Jialiang, Fei, Zhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922810/
https://www.ncbi.nlm.nih.gov/pubmed/35287697
http://dx.doi.org/10.1186/s12974-022-02428-8

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