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Evaluation of factors influencing expression and extraction of recombinant bacteriophage endolysins in Escherichia coli

BACKGROUND: Endolysins are peptidoglycan hydrolases with promising use as environment-friendly antibacterials mainly when used topically. However, in general, endolysin expression is hampered by its low solubility. Thus, a critical point in endolysin industrial production is optimizing their express...

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Detalles Bibliográficos
Autores principales: Balaban, Cecilia Lucía, Suárez, Cristian Alejandro, Boncompain, Carina Andrea, Peressutti-Bacci, Natalia, Ceccarelli, Eduardo Augusto, Morbidoni, Héctor Ricardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922839/
https://www.ncbi.nlm.nih.gov/pubmed/35292023
http://dx.doi.org/10.1186/s12934-022-01766-9