Cargando…
Clear cell carcinoma arising from abdominal wall endometriosis—a report on two cases and literature review
BACKGROUND: Malignant transformation of abdominal wall endometriosis is extremely rare. Clear cell carcinoma and endometrioid carcinoma are the two most prevalent histological subtypes of malignant endometriosis. To date, approximately, thirty cases of clear cell carcinoma arising from abdominal wal...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922864/ https://www.ncbi.nlm.nih.gov/pubmed/35292079 http://dx.doi.org/10.1186/s12957-022-02553-x |
_version_ | 1784669580037193728 |
---|---|
author | Bahall, Vishal De Barry, Lance Rampersad, Arlene |
author_facet | Bahall, Vishal De Barry, Lance Rampersad, Arlene |
author_sort | Bahall, Vishal |
collection | PubMed |
description | BACKGROUND: Malignant transformation of abdominal wall endometriosis is extremely rare. Clear cell carcinoma and endometrioid carcinoma are the two most prevalent histological subtypes of malignant endometriosis. To date, approximately, thirty cases of clear cell carcinoma arising from abdominal wall endometriosis have been described worldwide. CASE PRESENTATION: We report two cases of clear cell carcinoma developing postoperatively in the anterior abdominal wall in women with a history of extensive endometriosis. Histopathology of the resected abdominal wall tumor demonstrated benign endometriosis contiguous with features of clear cell carcinoma. These histological features satisfied Sampson’s criteria which are required for diagnosing malignant endometriosis. Both patients were successfully managed with platinum-based adjuvant chemotherapy following cytoreductive surgery. CONCLUSION: Clear cell carcinoma arising from the abdominal wall endometriosis is a rare, highly aggressive cancer with a propensity to recur or metastasize. Due to the limited publications on this clinical entity, there are no clearly established protocols regarding adjuvant treatment, and an evaluation of prognostic factors is lacking. Clinicians must have a high index of suspicion for malignant endometriosis of the abdominal wall, particularly in patients with an abdominal wall mass, prior abdominal surgery, and long-standing endometriosis. By presenting our case, we expect to raise awareness and study of this rare endometriosis-related neoplasm. |
format | Online Article Text |
id | pubmed-8922864 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-89228642022-03-22 Clear cell carcinoma arising from abdominal wall endometriosis—a report on two cases and literature review Bahall, Vishal De Barry, Lance Rampersad, Arlene World J Surg Oncol Case Report BACKGROUND: Malignant transformation of abdominal wall endometriosis is extremely rare. Clear cell carcinoma and endometrioid carcinoma are the two most prevalent histological subtypes of malignant endometriosis. To date, approximately, thirty cases of clear cell carcinoma arising from abdominal wall endometriosis have been described worldwide. CASE PRESENTATION: We report two cases of clear cell carcinoma developing postoperatively in the anterior abdominal wall in women with a history of extensive endometriosis. Histopathology of the resected abdominal wall tumor demonstrated benign endometriosis contiguous with features of clear cell carcinoma. These histological features satisfied Sampson’s criteria which are required for diagnosing malignant endometriosis. Both patients were successfully managed with platinum-based adjuvant chemotherapy following cytoreductive surgery. CONCLUSION: Clear cell carcinoma arising from the abdominal wall endometriosis is a rare, highly aggressive cancer with a propensity to recur or metastasize. Due to the limited publications on this clinical entity, there are no clearly established protocols regarding adjuvant treatment, and an evaluation of prognostic factors is lacking. Clinicians must have a high index of suspicion for malignant endometriosis of the abdominal wall, particularly in patients with an abdominal wall mass, prior abdominal surgery, and long-standing endometriosis. By presenting our case, we expect to raise awareness and study of this rare endometriosis-related neoplasm. BioMed Central 2022-03-15 /pmc/articles/PMC8922864/ /pubmed/35292079 http://dx.doi.org/10.1186/s12957-022-02553-x Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Case Report Bahall, Vishal De Barry, Lance Rampersad, Arlene Clear cell carcinoma arising from abdominal wall endometriosis—a report on two cases and literature review |
title | Clear cell carcinoma arising from abdominal wall endometriosis—a report on two cases and literature review |
title_full | Clear cell carcinoma arising from abdominal wall endometriosis—a report on two cases and literature review |
title_fullStr | Clear cell carcinoma arising from abdominal wall endometriosis—a report on two cases and literature review |
title_full_unstemmed | Clear cell carcinoma arising from abdominal wall endometriosis—a report on two cases and literature review |
title_short | Clear cell carcinoma arising from abdominal wall endometriosis—a report on two cases and literature review |
title_sort | clear cell carcinoma arising from abdominal wall endometriosis—a report on two cases and literature review |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922864/ https://www.ncbi.nlm.nih.gov/pubmed/35292079 http://dx.doi.org/10.1186/s12957-022-02553-x |
work_keys_str_mv | AT bahallvishal clearcellcarcinomaarisingfromabdominalwallendometriosisareportontwocasesandliteraturereview AT debarrylance clearcellcarcinomaarisingfromabdominalwallendometriosisareportontwocasesandliteraturereview AT rampersadarlene clearcellcarcinomaarisingfromabdominalwallendometriosisareportontwocasesandliteraturereview |