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Circ_0000064 promotes high glucose-induced renal tubular epithelial cells injury to facilitate diabetic nephropathy progression through miR-532-3p/ROCK1 axis

BACKGROUND: Circular RNA (circRNA) has been shown to mediate diabetic nephropathy (DN) development by regulating renal tubular epithelial cells (RTECs) injury. However, the role and mechanism of circ_0000064 in high glucose (HG)-induced RTECs injury have not been fully elucidated. METHODS: Human RTE...

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Detalles Bibliográficos
Autores principales: Wang, Huanlan, Huang, Shenghua, Hu, Taotao, Fei, Shizhi, Zhang, Huanqiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922934/
https://www.ncbi.nlm.nih.gov/pubmed/35291991
http://dx.doi.org/10.1186/s12902-022-00968-x

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