Accelerated epigenetic age and shortened telomere length based on DNA methylation in Nicolaides–Baraitser syndrome

BACKGROUND: Nicolaides–Baraitser syndrome (NCBRS) is a rare disorder characterized by neurodevelopmental delays, seizures, and diverse physical characteristics. The DNA methylation (DNAm) profile in NCBRS is significantly different. DNAm is linked to the biological aging of cells and the health risk...

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Detalles Bibliográficos
Autores principales: Shinko, Yutaka, Okazaki, Satoshi, Otsuka, Ikuo, Horai, Tadasu, Kim, Saehyeon, Tanifuji, Takaki, Hishimoto, Akitoyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922957/
https://www.ncbi.nlm.nih.gov/pubmed/35092358
http://dx.doi.org/10.1002/mgg3.1876

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922957/
https://www.ncbi.nlm.nih.gov/pubmed/35092358
http://dx.doi.org/10.1002/mgg3.1876

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