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Accelerated epigenetic age and shortened telomere length based on DNA methylation in Nicolaides–Baraitser syndrome
BACKGROUND: Nicolaides–Baraitser syndrome (NCBRS) is a rare disorder characterized by neurodevelopmental delays, seizures, and diverse physical characteristics. The DNA methylation (DNAm) profile in NCBRS is significantly different. DNAm is linked to the biological aging of cells and the health risk...
Autores principales: | Shinko, Yutaka, Okazaki, Satoshi, Otsuka, Ikuo, Horai, Tadasu, Kim, Saehyeon, Tanifuji, Takaki, Hishimoto, Akitoyo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922957/ https://www.ncbi.nlm.nih.gov/pubmed/35092358 http://dx.doi.org/10.1002/mgg3.1876 |
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