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scREMOTE: Using multimodal single cell data to predict regulatory gene relationships and to build a computational cell reprogramming model

Cell reprogramming offers a potential treatment to many diseases, by regenerating specialized somatic cells. Despite decades of research, discovering the transcription factors that promote cell reprogramming has largely been accomplished through trial and error, a time-consuming and costly method. A...

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Detalles Bibliográficos
Autores principales: Tran, Andy, Yang, Pengyi, Yang, Jean Y H, Ormerod, John T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8923006/
https://www.ncbi.nlm.nih.gov/pubmed/35300460
http://dx.doi.org/10.1093/nargab/lqac023

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