Geneticin shows selective antiviral activity against SARS-CoV-2 by interfering with programmed −1 ribosomal frameshifting

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SARS-CoV-2 is currently causing an unprecedented pandemic. While vaccines are massively deployed, we still lack effective large-scale antiviral therapies. In the quest for antivirals targeting conserved structures, we focused on molecules able to bind viral RNA secondary structures. Aminoglycosides...

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Detalles Bibliográficos
Autores principales: Varricchio, Carmine, Mathez, Gregory, Pillonel, Trestan, Bertelli, Claire, Kaiser, Laurent, Tapparel, Caroline, Brancale, Andrea, Cagno, Valeria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8923105/
https://www.ncbi.nlm.nih.gov/pubmed/35291297
http://dx.doi.org/10.1101/2022.03.08.483429
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