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The Fibrillin‐1/VEGFR2/STAT2 signaling axis promotes chemoresistance via modulating glycolysis and angiogenesis in ovarian cancer organoids and cells

BACKGROUND: Chemotherapy resistance is a primary reason of ovarian cancer therapy failure; hence it is important to investigate the underlying mechanisms of chemotherapy resistance and develop novel potential therapeutic targets. METHODS: RNA sequencing of cisplatin‐resistant and ‐sensitive (chemore...

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Detalles Bibliográficos
Autores principales: Wang, Ziliang, Chen, Wei, Zuo, Ling, Xu, Midie, Wu, Yong, Huang, Jiami, Zhang, Xu, Li, Yongheng, Wang, Jing, Chen, Jing, Wang, Husheng, Sun, Huizhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8923131/
https://www.ncbi.nlm.nih.gov/pubmed/35234370
http://dx.doi.org/10.1002/cac2.12274

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