Extracellular Matrix Stiffness and TGFβ2 Regulate YAP/TAZ Activity in Human Trabecular Meshwork Cells

Primary open-angle glaucoma progression is associated with increased human trabecular meshwork (HTM) stiffness and elevated transforming growth factor beta 2 (TGFβ2) levels in the aqueous humor. Increased transcriptional activity of Yes-associated protein (YAP) and transcriptional coactivator with P...

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Detalles Bibliográficos
Autores principales: Li, Haiyan, Raghunathan, VijayKrishna, Stamer, W. Daniel, Ganapathy, Preethi S., Herberg, Samuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8923257/
https://www.ncbi.nlm.nih.gov/pubmed/35300422
http://dx.doi.org/10.3389/fcell.2022.844342

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8923257/
https://www.ncbi.nlm.nih.gov/pubmed/35300422
http://dx.doi.org/10.3389/fcell.2022.844342

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