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Autocrine signaling can explain the emergence of Allee effects in cancer cell populations

In many human cancers, the rate of cell growth depends crucially on the size of the tumor cell population. Low, zero, or negative growth at low population densities is known as the Allee effect; this effect has been studied extensively in ecology, but so far lacks a good explanation in the cancer se...

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Detalles Bibliográficos
Autores principales: Gerlee, Philip, Altrock, Philipp M., Malik, Adam, Krona, Cecilia, Nelander, Sven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8923455/
https://www.ncbi.nlm.nih.gov/pubmed/35239640
http://dx.doi.org/10.1371/journal.pcbi.1009844

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