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Autocrine signaling can explain the emergence of Allee effects in cancer cell populations
In many human cancers, the rate of cell growth depends crucially on the size of the tumor cell population. Low, zero, or negative growth at low population densities is known as the Allee effect; this effect has been studied extensively in ecology, but so far lacks a good explanation in the cancer se...
Autores principales: | Gerlee, Philip, Altrock, Philipp M., Malik, Adam, Krona, Cecilia, Nelander, Sven |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8923455/ https://www.ncbi.nlm.nih.gov/pubmed/35239640 http://dx.doi.org/10.1371/journal.pcbi.1009844 |
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