LncCCAT1 interaction protein PKM2 upregulates SREBP2 phosphorylation to promote osteosarcoma tumorigenesis by enhancing the Warburg effect and lipogenesis

Pyruvate kinase M2 (PKM2) plays an important role in the consumption of glucose and the production of lactic acid, the striking feature of cancer metabolism. The association of PKM2 with osteosarcoma (OS) has been reported but its role in OS has yet to be elucidated. To study this, PKM2-bound RNAs i...

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Detalles Bibliográficos
Autores principales: Pu, Feifei, Liu, Jianxiang, Jing, Doudou, Chen, Fengxia, Huang, Xin, Shi, Deyao, Wu, Wei, Lin, Hui, Zhao, Lei, Zhang, Zhenhao, Lv, Xiao, Wang, Baichuan, Zhang, Zhicai, Shao, Zengwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8923656/
https://www.ncbi.nlm.nih.gov/pubmed/35244192
http://dx.doi.org/10.3892/ijo.2022.5334

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