Cargando…

Mannan-Binding Lectin Regulates the Th17/Treg Axis Through JAK/STAT and TGF-β/SMAD Signaling Against Candida albicans Infection

BACKGROUND: Mannan-binding lectin (MBL) is a key molecule in innate immunity and activates the lectin complement pathway, which plays an important role in resisting Candida albicans (C. albicans) infection. However, the underlying mechanism of this resistance to infection remains unclear. METHODS: I...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Fanping, Yang, Yonghui, Li, Zhixin, Wang, Yan, Zhang, Zhenchao, Zhang, Wei, Mu, Yonghui, Yang, Jingwen, Yu, Lili, Wang, Mingyong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8923702/ https://www.ncbi.nlm.nih.gov/pubmed/35300210 http://dx.doi.org/10.2147/JIR.S344489

Ejemplares similares

Mannan-Binding Lectin Suppresses Peptidoglycan-Induced TLR2 Activation and Inflammatory Responses
por: Wang, Fanping, et al.
Publicado: (2019)

Mannan-Binding Lectin Inhibits Candida albicans-Induced Cellular Responses in PMA-Activated THP-1 Cells through Toll-Like Receptor 2 and Toll-Like Receptor 4
por: Wang, Mingyong, et al.
Publicado: (2013)

Mannan-binding lectin ameliorates renal fibrosis by suppressing macrophage-to-myofibroblast transition
por: Xu, Li, et al.
Publicado: (2023)

Mannan-binding lectin regulates dendritic cell maturation and cytokine production induced by lipopolysaccharide
por: Wang, Mingyong, et al.
Publicado: (2011)

Mannan-Binding Lectin in Cardiovascular Disease
por: Pągowska-Klimek, Izabela, et al.
Publicado: (2014)

Mannan-Binding Lectin Attenuates Inflammatory Arthritis Through the Suppression of Osteoclastogenesis
por: Dong, Lijun, et al.
Publicado: (2019)

Clinical manifestations of mannan-binding lectin deficiency
por: Thiel, S., et al.
Publicado: (2006)

Candida albicans Hypha Formation and Mannan Masking of β-Glucan Inhibit Macrophage Phagosome Maturation
por: Bain, Judith M., et al.
Publicado: (2014)

Diabetes Is Associated with Increased Autoreactivity of Mannan-Binding Lectin
por: Axelgaard, Esben, et al.
Publicado: (2017)

Applications of mannose-binding lectins and mannan glycoconjugates in nanomedicine
por: Gupta, Anita, et al.
Publicado: (2022)

Brothers in Arms: Th17 and Treg Responses in Candida albicans Immunity
por: Whibley, Natasha, et al.
Publicado: (2014)

The Role of Mannan-Binding Lectin (MBL) Gene Polymorphism in Ulcerative Colitis
por: Wang, Fang-Yu, et al.
Publicado: (2008)

A Multifunctional Mannosyltransferase Family in Candida albicans Determines Cell Wall Mannan Structure and Host-Fungus Interactions
por: Mora-Montes, Héctor M., et al.
Publicado: (2010)

Identification of a new DC-SIGN binding pentamannoside epitope within the complex structure of Candida albicans mannan
por: Krylov, Vadim B., et al.
Publicado: (2023)

Candida albicans-induced activation of the TGF-β/Smad pathway and upregulation of IL-6 may contribute to intrauterine adhesion
por: Zhao, Xingping, et al.
Publicado: (2023)

Mannan-Binding Lectin Deficiency Limits Inflammation-induced Myeloid-Derived Suppressor Cells Expansion via Modulating Tumor Necrosis Factor Alpha-triggered Apoptosis
por: Dong, Lijun, et al.
Publicado: (2022)

Mannan-binding lectin and procalcitonin measurement for prediction of postoperative infection
por: Siassi, Michael, et al.
Publicado: (2005)

Mannan-binding lectin in cerebrospinal fluid: a leptomeningeal protein
por: Reiber, Hansotto, et al.
Publicado: (2012)

Mannan binding lectin triggers mobilization of hematopoietic stem cells
por: Adamiak, Mateusz, et al.
Publicado: (2017)

JAK/STAT signaling in diabetic kidney disease
por: Liu, Yingjun, et al.
Publicado: (2023)

Correction: Mannan-binding lectin and procalcitonin measurement for prediction of postoperative infection
por: Siassi, Michael, et al.
Publicado: (2005)

Candida albicans mannans mediate Streptococcus mutans exoenzyme GtfB binding to modulate cross-kingdom biofilm development in vivo
por: Hwang, Geelsu, et al.
Publicado: (2017)

Immunochemistry of pathogenic yeast, Candida species, focusing on mannan
por: SHIBATA, Nobuyuki, et al.
Publicado: (2012)

Flexibility in Mannan-Binding Lectin-Associated Serine Proteases-1 and -2 Provides Insight on Lectin Pathway Activation
por: Nan, Ruodan, et al.
Publicado: (2017)

Complement Receptor 1/Cd35 Is a Receptor for Mannan-Binding Lectin
por: Ghiran, Ionita, et al.
Publicado: (2000)

Effect of Optimization of Glycaemic Control on Mannan-Binding Lectin in Type 1 Diabetes
por: Dørflinger, Gry Høst, et al.
Publicado: (2017)

Solanine Inhibits Immune Escape Mediated by Hepatoma Treg Cells via the TGFβ/Smad Signaling Pathway
por: Gao, Juwei, et al.
Publicado: (2020)

Serum mannan-binding lectin-associated serine proteases in early pregnancy for gestational diabetes in Chinese pregnant women
por: Gao, Ming, et al.
Publicado: (2023)

Icariin Attenuates Monocrotaline-Induced Pulmonary Arterial Hypertension via the Inhibition of TGF-β1/Smads Pathway in Rats
por: Xiang, Yijia, et al.
Publicado: (2020)

M2-Type Macrophages Induce Tregs Generation by Activating the TGF-β/Smad Signalling Pathway to Promote Colorectal Cancer Development
por: Ma, Xueqian, et al.
Publicado: (2021)

Direct Blood Culturing of Candida spp. on Solid Medium by a Rapid Enrichment Method with Magnetic Beads Coated with Recombinant Human Mannan-Binding Lectin
por: Chen, Xiao-Li, et al.
Publicado: (2020)

Mannan binding lectin as an adjunct to risk assessment for myocardial infarction in individuals with enhanced risk
por: Saevarsdottir, Saedis, et al.
Publicado: (2005)

Lysyl Hydroxylase 3 Modifies Lysine Residues to Facilitate Oligomerization of Mannan-Binding Lectin
por: Risteli, Maija, et al.
Publicado: (2014)

High normal TSH is associated with lower mannan-binding lectin in women of childbearing age
por: Karbownik-Lewinska, Malgorzata, et al.
Publicado: (2020)

TGF‐β/Smad and JAK/STAT pathways are involved in the anti‐fibrotic effects of propylene glycol alginate sodium sulphate on hepatic fibrosis
por: Xu, Shizan, et al.
Publicado: (2020)

Natural Flavonoid Pectolinarigenin Alleviated Hyperuricemic Nephropathy via Suppressing TGFβ/SMAD3 and JAK2/STAT3 Signaling Pathways
por: Ren, Qian, et al.
Publicado: (2022)

Biochemical characterization of recombinant Candida albicans mannosyltransferases Mnt1, Mnt2 and Mnt5 reveals new functions in O- and N-mannan biosynthesis
por: Díaz-Jiménez, Diana F., et al.
Publicado: (2012)

Dissection of the anti-Candida albicans mannan immune response using synthetic oligomannosides reveals unique properties of β-1,2 mannotriose protective epitopes
por: Sendid, Boualem, et al.
Publicado: (2021)

Association between Low Levels of Mannan-Binding Lectin and Markers of Autoimmune Thyroid Disease in Pregnancy
por: Potlukova, Eliska, et al.
Publicado: (2013)

Defective activities, but not secretions, resulting from gene point mutations of human mannan-binding lectin
por: LIU, YING, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_aarc7pg6hlhoadkab3i07pfbev