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Structure and conformational dynamics of Clostridioides difficile toxin A

Clostridioides difficile toxin A and B (TcdA and TcdB) are two major virulence factors responsible for diseases associated with C. difficile infection (CDI). Here, we report the 3.18-Å resolution crystal structure of a TcdA fragment (residues L843–T2481), which advances our understanding of the comp...

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Detalles Bibliográficos
Autores principales:	Chen, Baohua, Basak, Sujit, Chen, Peng, Zhang, Changcheng, Perry, Kay, Tian, Songhai, Yu, Clinton, Dong, Min, Huang, Lan, Bowen, Mark E, Jin, Rongsheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Life Science Alliance LLC 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8924006/ https://www.ncbi.nlm.nih.gov/pubmed/35292538 http://dx.doi.org/10.26508/lsa.202201383

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