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Mre11 exonuclease activity promotes irreversible mitotic progression under replication stress
Mre11 is a versatile exo-/endonuclease involved in multiple aspects of DNA replication and repair, such as DSB end processing and checkpoint activation. We previously demonstrated that forced mitotic entry drives replisome disassembly at stalled replication forks in Xenopus egg extracts. Here, we ex...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Life Science Alliance LLC
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8924007/ https://www.ncbi.nlm.nih.gov/pubmed/35292537 http://dx.doi.org/10.26508/lsa.202101249 |