Abnormalities in Cortical GABAergic Interneurons of the Primary Motor Cortex Caused by Lis1 (Pafah1b1) Mutation Produce a Non-drastic Functional Phenotype

LIS1 (PAFAH1B1) plays a major role in the developing cerebral cortex, and haploinsufficient mutations cause human lissencephaly type 1. We have studied morphological and functional properties of the cerebral cortex of mutant mice harboring a deletion in the first exon of the mouse Lis1 (Pafah1b1) ge...

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Detalles Bibliográficos
Autores principales: Domínguez-Sala, E., Valdés-Sánchez, L., Canals, S., Reiner, O., Pombero, A., García-López, R., Estirado, A., Pastor, D., Geijo-Barrientos, E., Martínez, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8924048/
https://www.ncbi.nlm.nih.gov/pubmed/35309904
http://dx.doi.org/10.3389/fcell.2022.769853

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