Eosinophil-Derived Osteopontin Induces the Expression of Pro-Inflammatory Mediators and Stimulates Extracellular Matrix Production in Nasal Fibroblasts: The Role of Osteopontin in Eosinophilic Chronic Rhinosinusitis

BACKGROUND: Eosinophilic chronic rhinosinusitis (ECRS) is a subtype of chronic rhinosinusitis (CRS) and is a refractory or intractable disease. However, a reliable clinical marker or an effective treatment strategy has not yet been established. ECRS is accompanied by excessive eosinophil infiltratio...

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Detalles Bibliográficos
Autores principales: Yang, Hyun-Woo, Park, Joo-Hoo, Jo, Min-Sik, Shin, Jae-Min, Kim, Dae Woo, Park, Il-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8924074/
https://www.ncbi.nlm.nih.gov/pubmed/35309360
http://dx.doi.org/10.3389/fimmu.2022.777928

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