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Nobel somatosensations and pain
The Nobel prices 2021 for Physiology and Medicine have been awarded to David Julius and Ardem Patapoutian "for their discoveries of receptors for temperature and touch", TRPV1 and PIEZO1/2. The present review tells the past history of the capsaicin receptor, covers further selected TRP cha...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8924131/ https://www.ncbi.nlm.nih.gov/pubmed/35157132 http://dx.doi.org/10.1007/s00424-022-02667-x |
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author | Reeh, Peter W. Fischer, Michael J. M. |
author_facet | Reeh, Peter W. Fischer, Michael J. M. |
author_sort | Reeh, Peter W. |
collection | PubMed |
description | The Nobel prices 2021 for Physiology and Medicine have been awarded to David Julius and Ardem Patapoutian "for their discoveries of receptors for temperature and touch", TRPV1 and PIEZO1/2. The present review tells the past history of the capsaicin receptor, covers further selected TRP channels, TRPA1 in particular, and deals with mechanosensitivity in general and mechanical hyperalgesia in particular. Other achievements of the laureates and translational aspects of their work are shortly treated. |
format | Online Article Text |
id | pubmed-8924131 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-89241312022-03-17 Nobel somatosensations and pain Reeh, Peter W. Fischer, Michael J. M. Pflugers Arch Invited Review The Nobel prices 2021 for Physiology and Medicine have been awarded to David Julius and Ardem Patapoutian "for their discoveries of receptors for temperature and touch", TRPV1 and PIEZO1/2. The present review tells the past history of the capsaicin receptor, covers further selected TRP channels, TRPA1 in particular, and deals with mechanosensitivity in general and mechanical hyperalgesia in particular. Other achievements of the laureates and translational aspects of their work are shortly treated. Springer Berlin Heidelberg 2022-02-14 2022 /pmc/articles/PMC8924131/ /pubmed/35157132 http://dx.doi.org/10.1007/s00424-022-02667-x Text en © The Author(s) 2022, corrected publication 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Invited Review Reeh, Peter W. Fischer, Michael J. M. Nobel somatosensations and pain |
title | Nobel somatosensations and pain |
title_full | Nobel somatosensations and pain |
title_fullStr | Nobel somatosensations and pain |
title_full_unstemmed | Nobel somatosensations and pain |
title_short | Nobel somatosensations and pain |
title_sort | nobel somatosensations and pain |
topic | Invited Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8924131/ https://www.ncbi.nlm.nih.gov/pubmed/35157132 http://dx.doi.org/10.1007/s00424-022-02667-x |
work_keys_str_mv | AT reehpeterw nobelsomatosensationsandpain AT fischermichaeljm nobelsomatosensationsandpain |