Molecular basis for allosteric agonism and G protein subtype selectivity of galanin receptors

Peptide hormones and neuropeptides are complex signaling molecules that predominately function through G protein-coupled receptors (GPCRs). Two unanswered questions remaining in the field of peptide-GPCR signaling systems pertain to the basis for the diverse binding modes of peptide ligands and the...

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Detalles Bibliográficos
Autores principales: Duan, Jia, Shen, Dan-Dan, Zhao, Tingting, Guo, Shimeng, He, Xinheng, Yin, Wanchao, Xu, Peiyu, Ji, Yujie, Chen, Li-Nan, Liu, Jinyu, Zhang, Huibing, Liu, Qiufeng, Shi, Yi, Cheng, Xi, Jiang, Hualiang, Eric Xu, H., Zhang, Yan, Xie, Xin, Jiang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8924211/
https://www.ncbi.nlm.nih.gov/pubmed/35292680
http://dx.doi.org/10.1038/s41467-022-29072-3

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