Tau deposition patterns are associated with functional connectivity in primary tauopathies

Tau pathology is the main driver of neuronal dysfunction in 4-repeat tauopathies, including cortico-basal degeneration and progressive supranuclear palsy. Tau is assumed to spread prion-like across connected neurons, but the mechanisms of tau propagation are largely elusive in 4-repeat tauopathies,...

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Detalles Bibliográficos
Autores principales: Franzmeier, Nicolai, Brendel, Matthias, Beyer, Leonie, Slemann, Luna, Kovacs, Gabor G., Arzberger, Thomas, Kurz, Carolin, Respondek, Gesine, Lukic, Milica J., Biel, Davina, Rubinski, Anna, Frontzkowski, Lukas, Hummel, Selina, Müller, Andre, Finze, Anika, Palleis, Carla, Joseph, Emanuel, Weidinger, Endy, Katzdobler, Sabrina, Song, Mengmeng, Biechele, Gloria, Kern, Maike, Scheifele, Maximilian, Rauchmann, Boris-Stephan, Perneczky, Robert, Rullman, Michael, Patt, Marianne, Schildan, Andreas, Barthel, Henryk, Sabri, Osama, Rumpf, Jost J., Schroeter, Matthias L., Classen, Joseph, Villemagne, Victor, Seibyl, John, Stephens, Andrew W., Lee, Edward B., Coughlin, David G., Giese, Armin, Grossman, Murray, McMillan, Corey T., Gelpi, Ellen, Molina-Porcel, Laura, Compta, Yaroslau, van Swieten, John C., Laat, Laura Donker, Troakes, Claire, Al-Sarraj, Safa, Robinson, John L., Xie, Sharon X., Irwin, David J., Roeber, Sigrun, Herms, Jochen, Simons, Mikael, Bartenstein, Peter, Lee, Virginia M., Trojanowski, John Q., Levin, Johannes, Höglinger, Günter, Ewers, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8924216/
https://www.ncbi.nlm.nih.gov/pubmed/35292638
http://dx.doi.org/10.1038/s41467-022-28896-3

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