Myosin VI regulates the spatial organisation of mammalian transcription initiation

During transcription, RNA Polymerase II (RNAPII) is spatially organised within the nucleus into clusters that correlate with transcription activity. While this is a hallmark of genome regulation in mammalian cells, the mechanisms concerning the assembly, organisation and stability remain unknown. He...

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Detalles Bibliográficos
Autores principales: Hari-Gupta, Yukti, Fili, Natalia, dos Santos, Ália, Cook, Alexander W., Gough, Rosemarie E., Reed, Hannah C. W., Wang, Lin, Aaron, Jesse, Venit, Tomas, Wait, Eric, Grosse-Berkenbusch, Andreas, Gebhardt, J. Christof M., Percipalle, Piergiorgio, Chew, Teng-Leong, Martin-Fernandez, Marisa, Toseland, Christopher P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8924246/
https://www.ncbi.nlm.nih.gov/pubmed/35292632
http://dx.doi.org/10.1038/s41467-022-28962-w

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