Targeted Tshz3 deletion in corticostriatal circuit components segregates core autistic behaviors

We previously linked TSHZ3 haploinsufficiency to autism spectrum disorder (ASD) and showed that embryonic or postnatal Tshz3 deletion in mice results in behavioral traits relevant to the two core domains of ASD, namely social interaction deficits and repetitive behaviors. Here, we provide evidence t...

Descripción completa

Detalles Bibliográficos
Autores principales: Caubit, Xavier, Gubellini, Paolo, Roubertoux, Pierre L., Carlier, Michèle, Molitor, Jordan, Chabbert, Dorian, Metwaly, Mehdi, Salin, Pascal, Fatmi, Ahmed, Belaidouni, Yasmine, Brosse, Lucie, Kerkerian-Le Goff, Lydia, Fasano, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8924251/
https://www.ncbi.nlm.nih.gov/pubmed/35292625
http://dx.doi.org/10.1038/s41398-022-01865-6

Ejemplares similares

Ejemplares similares