Negative Modulation of Macroautophagy by Stabilized HERPUD1 is Counteracted by an Increased ER-Lysosomal Network With Impact in Drug-Induced Stress Cell Survival

Macroautophagy and the ubiquitin proteasome system work as an interconnected network in the maintenance of cellular homeostasis. Indeed, efficient activation of macroautophagy upon nutritional deprivation is sustained by degradation of preexisting proteins by the proteasome. However, the specific su...

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Detalles Bibliográficos
Autores principales: Vargas, Gabriela, Cortés, Omar, Arias-Muñoz, Eloisa, Hernández, Sergio, Cerda-Troncoso, Cristobal, Hernández, Laura, González, Alexis E., Tatham, Michael H., Bustamante, Hianara A., Retamal, Claudio, Cancino, Jorge, Varas-Godoy, Manuel, Hay, Ronald T., Rojas-Fernández, Alejandro, Cavieres, Viviana A., Burgos, Patricia V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8924303/
https://www.ncbi.nlm.nih.gov/pubmed/35309917
http://dx.doi.org/10.3389/fcell.2022.743287

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