Cargando…
Zebrafish as an experimental model for the simulation of neurological and craniofacial disorders
Zebrafish have gained momentum as a leading experimental model in recent years. At present, the zebrafish vertebrate model is increasingly used due to its multifactorial similarities to humans that include genetic, organ, and cellular factors. With the emergence of novel research techniques that are...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Veterinary World
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8924399/ https://www.ncbi.nlm.nih.gov/pubmed/35369579 http://dx.doi.org/10.14202/vetworld.2022.22-29 |
_version_ | 1784669846661758976 |
---|---|
author | Rai, Ashwin Rohan Joy, Teresa Rashmi, K. S. Rai, Rajalakshmi Vinodini, N. A. J. Jiji, P. |
author_facet | Rai, Ashwin Rohan Joy, Teresa Rashmi, K. S. Rai, Rajalakshmi Vinodini, N. A. J. Jiji, P. |
author_sort | Rai, Ashwin Rohan |
collection | PubMed |
description | Zebrafish have gained momentum as a leading experimental model in recent years. At present, the zebrafish vertebrate model is increasingly used due to its multifactorial similarities to humans that include genetic, organ, and cellular factors. With the emergence of novel research techniques that are very expensive, it is necessary to develop affordable and valid experimental models. This review aimed to highlight some of the most important similarities between zebrafish and humans by emphasizing the relevance of the first in simulating neurological disorders and craniofacial deformity. |
format | Online Article Text |
id | pubmed-8924399 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Veterinary World |
record_format | MEDLINE/PubMed |
spelling | pubmed-89243992022-04-01 Zebrafish as an experimental model for the simulation of neurological and craniofacial disorders Rai, Ashwin Rohan Joy, Teresa Rashmi, K. S. Rai, Rajalakshmi Vinodini, N. A. J. Jiji, P. Vet World Review Article Zebrafish have gained momentum as a leading experimental model in recent years. At present, the zebrafish vertebrate model is increasingly used due to its multifactorial similarities to humans that include genetic, organ, and cellular factors. With the emergence of novel research techniques that are very expensive, it is necessary to develop affordable and valid experimental models. This review aimed to highlight some of the most important similarities between zebrafish and humans by emphasizing the relevance of the first in simulating neurological disorders and craniofacial deformity. Veterinary World 2022-01 2022-01-11 /pmc/articles/PMC8924399/ /pubmed/35369579 http://dx.doi.org/10.14202/vetworld.2022.22-29 Text en Copyright: © Rai, et al. https://creativecommons.org/licenses/by/4.0/Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Review Article Rai, Ashwin Rohan Joy, Teresa Rashmi, K. S. Rai, Rajalakshmi Vinodini, N. A. J. Jiji, P. Zebrafish as an experimental model for the simulation of neurological and craniofacial disorders |
title | Zebrafish as an experimental model for the simulation of neurological and craniofacial disorders |
title_full | Zebrafish as an experimental model for the simulation of neurological and craniofacial disorders |
title_fullStr | Zebrafish as an experimental model for the simulation of neurological and craniofacial disorders |
title_full_unstemmed | Zebrafish as an experimental model for the simulation of neurological and craniofacial disorders |
title_short | Zebrafish as an experimental model for the simulation of neurological and craniofacial disorders |
title_sort | zebrafish as an experimental model for the simulation of neurological and craniofacial disorders |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8924399/ https://www.ncbi.nlm.nih.gov/pubmed/35369579 http://dx.doi.org/10.14202/vetworld.2022.22-29 |
work_keys_str_mv | AT raiashwinrohan zebrafishasanexperimentalmodelforthesimulationofneurologicalandcraniofacialdisorders AT joyteresa zebrafishasanexperimentalmodelforthesimulationofneurologicalandcraniofacialdisorders AT rashmiks zebrafishasanexperimentalmodelforthesimulationofneurologicalandcraniofacialdisorders AT rairajalakshmi zebrafishasanexperimentalmodelforthesimulationofneurologicalandcraniofacialdisorders AT vinodinina zebrafishasanexperimentalmodelforthesimulationofneurologicalandcraniofacialdisorders AT jjijip zebrafishasanexperimentalmodelforthesimulationofneurologicalandcraniofacialdisorders |