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Natural antibodies and CRP drive anaphylatoxin production by urate crystals

In gout, crystallization of uric acid in the form of monosodium urate (MSU) leads to a painful inflammatory response. MSU crystals induce inflammation by activating the complement system and various immune cell types, and by inducing necrotic cell death. We previously found that the soluble pattern...

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Detalles Bibliográficos
Autores principales:	Wessig, Anne Kathrin, Hoffmeister, Leonie, Klingberg, Annika, Alberts, Anika, Pich, Andreas, Brand, Korbinian, Witte, Torsten, Neumann, Konstantin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8924570/ https://www.ncbi.nlm.nih.gov/pubmed/35296708 http://dx.doi.org/10.1038/s41598-022-08311-z

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