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Dot6/Tod6 degradation fine-tunes the repression of ribosome biogenesis under nutrient-limited conditions
Ribosome biogenesis (Ribi) is a complex and energy-consuming process, and should therefore be repressed under nutrient-limited conditions to minimize unnecessary cellular energy consumption. In yeast, the transcriptional repressors Dot6 and Tod6 are phosphorylated and inactivated by the TORC1 pathwa...
Autores principales: | Kusama, Kino, Suzuki, Yuta, Kurita, Ena, Kawarasaki, Tomoyuki, Obara, Keisuke, Okumura, Fumihiko, Kamura, Takumi, Nakatsukasa, Kunio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8924686/ https://www.ncbi.nlm.nih.gov/pubmed/35310337 http://dx.doi.org/10.1016/j.isci.2022.103986 |
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