Cargando…

The Effects of a Meldonium Pre-Treatment on the Course of the LPS-Induced Sepsis in Rats

A dysregulated and overwhelming response to an infection accompanied by the exaggerated pro-inflammatory state and metabolism disturbance leads to the fatal outcome in sepsis. Previously we showed that meldonium, an anti-ischemic drug clinically used to treat myocardial and cerebral ischemia, strong...

Descripción completa

Detalles Bibliográficos
Autores principales:	Đurašević, Siniša, Ružičić, Aleksandra, Lakić, Iva, Tosti, Tomislav, Đurović, Saša, Glumac, Sofija, Pejić, Snežana, Todorović, Ana, Drakulić, Dunja, Stanković, Sanja, Jasnić, Nebojša, Đorđević, Jelena, Todorović, Zoran
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8924897/ https://www.ncbi.nlm.nih.gov/pubmed/35216510 http://dx.doi.org/10.3390/ijms23042395

Ejemplares similares

The Effects of a Meldonium Pre-Treatment on the Course of the Faecal-Induced Sepsis in Rats
por: Đurašević, Siniša, et al.
Publicado: (2021)

The effects of meldonium on the acute ischemia/reperfusion liver injury in rats
por: Đurašević, Siniša, et al.
Publicado: (2021)

The Effects of Meldonium on the Renal Acute Ischemia/Reperfusion Injury in Rats
por: Đurašević, Siniša, et al.
Publicado: (2019)

Serum High-Mobility Group Box 1 and Heme Oxygenase-1 as Biomarkers in COVID-19 Patients at Hospital Admission
por: Grigorov, Ilijana, et al.
Publicado: (2023)

Lipids and Antiplatelet Therapy: Important Considerations and Future Perspectives
por: Đukanović, Nina, et al.
Publicado: (2021)

Effects of C60 Fullerene on Thioacetamide-Induced Rat Liver Toxicity and Gut Microbiome Changes
por: Đurašević, Siniša, et al.
Publicado: (2021)

Lipidomics Provides New Insight into Pathogenesis and Therapeutic Targets of the Ischemia—Reperfusion Injury
por: Todorović, Zoran, et al.
Publicado: (2021)

Mechanisms of Prostate Cancer Cells Survival and Their Therapeutic Targeting
por: Pejčić, Tomislav, et al.
Publicado: (2023)

The Expression of Insulin in the Central Nervous System: What Have We Learned So Far?
por: Dakic, Tamara, et al.
Publicado: (2023)

Immunohistochemical analysis of cyclin A expression in Wilms tumor
por: Radojević-Škodrić, Sanja, et al.
Publicado: (2019)

Antidepressants- and antipsychotics-induced hepatotoxicity
por: Todorović Vukotić, Nevena, et al.
Publicado: (2021)

Fasting Induced Cytoplasmic Fto expression in Some Neurons of Rat Hypothalamus
por: Vujovic, Predrag, et al.
Publicado: (2013)

Misuse of the metabolic modulator meldonium in sports
por: Lippi, Giuseppe, et al.
Publicado: (2017)

The effect of antioxidant status on overall survival in renal cell carcinoma
por: Pavlović, Ivan, et al.
Publicado: (2019)

Antioxidant enzymes and lipid peroxidation in endometrium of patients with polyps, myoma, hyperplasia and adenocarcinoma
por: Pejić, Snežana, et al.
Publicado: (2009)

Sex-Related Effects of Prenatal Stress on Region-Specific Expression of Monoamine Oxidase A and β Adrenergic Receptors in Rat Hearts
por: Jevjdovic, Tanja, et al.
Publicado: (2019)

Meldonium determination in milk and meat through UHPLC-HRMS
por: Temerdashev, A., et al.
Publicado: (2020)

Recovery of Polyphenolic Compounds and Vitamins from the Stinging Nettle Leaves: Thermal and Behavior and Biological Activity of Obtained Extracts
por: Đurović, Saša, et al.
Publicado: (2023)

Modulation of Hippocampal Antioxidant Defense System in Chronically Stressed Rats by Lithium
por: Popović, Nataša, et al.
Publicado: (2019)

Expression of Antioxidant Enzymes in Patients with Uterine Polyp, Myoma, Hyperplasia, and Adenocarcinoma
por: Todorović, Ana, et al.
Publicado: (2019)

Antioxidant defense system in the prefrontal cortex of chronically stressed rats treated with lithium
por: Gavrilović, Ljubica, et al.
Publicado: (2022)

Primary Metabolite Chromatographic Profiling as a Tool for Chemotaxonomic Classification of Seeds from Berry Fruits
por: Krstić, Đurđa, et al.
Publicado: (2022)

Adverse drug reactions and polypharmacy in cardiac patients
por: Mugoša, Snežana, et al.
Publicado: (2012)

Insights into the pharmacodynamics and pharmacokinetics of meldonium after exposure to acute high altitude
por: Liu, Fengying, et al.
Publicado: (2023)

Rosemary Essential Oils as a Promising Source of Bioactive Compounds: Chemical Composition, Thermal Properties, Biological Activity, and Gastronomical Perspectives
por: Micić, Darko, et al.
Publicado: (2021)

Risk factors for adverse drug reactions associated with clopidogrel therapy
por: Mugosa, Snezana, et al.
Publicado: (2022)

ABCB1 polymorphism in clopidogrel-treated Montenegrin patients
por: Mugosa, Snezana, et al.
Publicado: (2021)

Protective Effects of Meldonium in Experimental Models of Cardiovascular Complications with a Potential Application in COVID-19
por: Vilskersts, Reinis, et al.
Publicado: (2021)

Prognostic Value of Preoperative Neutrophil-to-lymphocyte Ratio for Prediction of Severe Cholecystitis
por: Micić, Dušan, et al.
Publicado: (2018)

Four Weeks of Aerobic Training Affects Cardiac Tissue Matrix Metalloproteinase, Lactate Dehydrogenase and Malate Dehydrogenase Enzymes Activities, and Hepatorenal Biomarkers in Experimental Hyperhomocysteinemia in Rats
por: Todorovic, Dusan, et al.
Publicado: (2021)

Factors affecting the development of adverse drug reactions to β-blockers in hospitalized cardiac patient population
por: Mugoša, Snežana, et al.
Publicado: (2016)

Normalization of heart rate variability with taurine and meldonium complex in post-infarction patients with type 2 diabetes mellitus
por: Belikova, Juliia, et al.
Publicado: (2019)

Meldonium Ameliorates Hypoxia-Induced Lung Injury and Oxidative Stress by Regulating Platelet-Type Phosphofructokinase-Mediated Glycolysis
por: Wang, Daohui, et al.
Publicado: (2022)

Meldonium Inhibits Cell Motility and Wound-Healing in Trabecular Meshwork Cells and Scleral Fibroblasts: Possible Applications in Glaucoma
por: Minnelli, Cristina, et al.
Publicado: (2023)

Prediction of Pest Insect Appearance Using Sensors and Machine Learning
por: Marković, Dušan, et al.
Publicado: (2021)

PB1917: EXPRESSION OF THE LONG NON-CODING RNA MALAT1 IN CHRONIC LYMPHOCYTIC LEUKEMIA
por: Karan-Đurašević, Teodora, et al.
Publicado: (2023)

Using the UTAUT model to analyze user intention to accept electronic payment systems in Serbia
por: Tomić, Nenad, et al.
Publicado: (2022)

Influence of IL-6, TNF-α and Hs-CRP on Insulin Sensitivity in Patients after Laparoscopic Cholecystectomy or Open Hernia Repair
por: Micić, Dušan, et al.
Publicado: (2018)

Acute Pretreatment with Chloroquine Attenuates Renal I/R Injury in Rats
por: Todorovic, Zoran, et al.
Publicado: (2014)

The Association between Participation in Fights and Bullying and the Perception of School, Teachers, and Peers among School-Age Children in Serbia
por: Stankovic, Sanja, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ailrppcc5fvr67jlnv7084seuv